I just went through 42 strings yesterday and cleaned them up. Whenever I saw a problem, I found the very first issue in the string where a bulb was a different color from what was expected, I cut it out and the bulb immediately before it. After joining up the pieces before and after the cutouts, I checked the resulting string out, if good -- I then added the two replacement bulbs at the end of the string, and checked one final time. I found maybe 15 strings with problems out of 42, but when I took out 2 at a time I only once had to repeat for a second problem bulb (pair).
part of my check-out procedure was to swing the string around a bit, and move it a bit to see if there was anything loose that might cause a bulb to act flakey.
i only think one bulb was bad when I removed 2, but it is hard to know if the first is leaving garbage for the second to pick up, or the second is creating its own garbage.