I use LSP, I don't have the issues some folks report.
Not to say I don't get the occasional, what the hell just happened moments. But I also had that with Vixen.
As far as your question:
* make sure you have current version
* Clean up any unused intervals
* Clear the spectral cache before optimize export
* I always add an interval as close to the beginning of sequence - ( there seems to be bug here and this is my work around for this)
* I also add an interval as close to the end of a sequence - again, just a work around.
* Export optimize
* Use optimize file to build you scheduler.
I have sync talking heads so any latency would be a major issue. The program is running spot on for me.