The rigid strips are 1M (39 inches) long and would not be fun to try to cut. Also, I'm not sure the end-to-end spacing can be squeezed to match the pixel to pixel spacing - meaning that the gap between the pixel at the end of one strip and the beginning of the next would be a little larger than the normal pixel spacing.
The Flexible strip can be cut about every 4 inches (3 pixel sets are tied to one control chip) - there are markings on the strip...
As for numbering the strings, that is up to you. The individual SSCs have to have their start address, count direction ( 1 to xxx or xxx to 1), and color order set (RGB, RBG, etc. depending on the node type). Personally I would want each node to have its own address for maximum flexibility - but that also takes more effort to program soooo many channels...
RM