Lag would be less than 1/30th of a second (time required to transmit a full pix universe)
If in hybrid mode, the next controller has to wait for all that data to pass before picking up its start address.
Also the delay would always be the same amount of time, so it could be adjusted out if it was that critical to you.
If using a full pix universe, it does take 1/30 sec to transmit, which means address 4096 is always about a 1/30th of a second behind address 1....